[Answer] John C. Calhoun became the first U.S. Vice President to do what?

Step 1 : Introduction to the question "John C. Calhoun became the first U.S. Vice President to do what?"

...After navigating strong ideological differences with President Andrew Jackson, John C. Calhoun became the first Vice President to resign from office on December 28, 1832. After his resignation, Calhoun took a seat in the Senate where he continued to have a contentious relationship with President Jackson and his supporters. The only other Vice President to resign was Spiro Agnew, Richard Nixon’s lieutenant, in 1973.

Step 2 : Answer to the question "John C. Calhoun became the first U.S. Vice President to do what?"

Resign:

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